Enzyme-catalyzed Asymmetric Hydrolysis of meso-Substrate. The Facile Synthesis of Both Enantiomers of cis-2,5-Disubstituted Tetrahydrofuran Derivatives
- 5 October 1988
- journal article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 17 (10) , 1717-1720
- https://doi.org/10.1246/cl.1988.1717
Abstract
The enzyme-catalyzed asymmetric hydrolysis of the meso-diesters derived from cis-2,5-bis(hydroxymethyl)tetrahydrofuran in presence of PLE, PPL, and CCL afforded the optically active half-esters. The both enantiomers of cis-5-(hydroxymethyl)tetrahydrofuran-2-carboxylic acid with high optical purity were prepared from the half-esters.This publication has 6 references indexed in Scilit:
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