Cyanide metabolism and vitamin B12 in multiple sclerosis.
- 1 October 1965
- journal article
- research article
- Published by BMJ in Journal of Neurology, Neurosurgery & Psychiatry
- Vol. 28 (5) , 426-428
- https://doi.org/10.1136/jnnp.28.5.426
Abstract
Cyanide-B12 metabolism was studied in 6 patients with multiple sclerosis and 7 controls with other neurological disorders. Plasma and urine cyanide and thiocyanate were measured and total serum B12 as well as serum B12 extractable without added cyanide were estimated using Laetobacillus leichmannii. Results indicated no abnormality of cyanide metabolism or total serum B12 concentrations related to multiple sclerosis. The significance of the slight increase in serum B12 extractable without cyanide in multiple sclerosis is uncertain at this time.This publication has 13 references indexed in Scilit:
- Observations on vitamin B12 in serum and cerebrospinal fluid in multiple sclerosisJournal of Clinical Pathology, 1965
- Isolation of Methylcobalamin from Natural Source MaterialNature, 1964
- Investigations into the Euglena method for the assay of the vitamin B12 in serumJournal of Clinical Pathology, 1964
- Neuropathological Changes in Chronic Cyanide IntoxicationNature, 1963
- On Vitamin B12 Forms in Human PlasmaActa Medica Scandinavica, 1963
- RETROBULBAR NEURITIS IN ADDISONIAN PERNICIOUS ANÆMIAThe Lancet, 1961
- RETROBULBAR NEURITIS IN ADDISONIAN PERNICIOUS ANAEMIAThe Lancet, 1961
- B12 Metabolism and Multiple Sclerosis.Experimental Biology and Medicine, 1960
- Studies on the metabolism of the carbon of cyanide and thiocyanateArchives of Biochemistry and Biophysics, 1952
- CYANIDE LEUCOENCEPHALOPATHY IN RATS AND OBSERVATIONS ON THE VASCULAR AND FERMENT HYPOTHESES OF DEMYELINATING DISEASESJournal of Neurology, Neurosurgery & Psychiatry, 1950