Cirrhosis and Hepatocellular Carcinoma in HIV-Infected Veterans With and Without the Hepatitis C Virus

Abstract
Of persons living with the human immunodeficiency virus (HIV) in the United States and western Europe, 30% or more are coinfected with the hepatitis C virus (HCV).1,2 Among persons with HCV only, 8% to 24% will develop cirrhosis over 2 to 3 decades following infection.3 Once cirrhosis is established, hepatocellular carcinoma (HCC), which has a median survival of 8 months, occurs annually in 1% to 4% of the subjects.4,5