TECHNETIUM-99M-LABELED METHYLENE DIPHOSPHONATE AND HYDROXYETHYLIDINE DIPHOSPHONATE BIOLOGICAL AND CLINICAL COMPARISON - CONCISE COMMUNICATION

  • 1 January 1979
    • journal article
    • research article
    • Vol. 20  (8) , 821-826
Abstract
The biologic and imaging characteristics of 99mTc MDP [methylene diphosphonate] and 99mTc HEDP [hydroxyethylidine diphosphonate] were compared in 10 patients. 99mTc MDP exhibited lower blood activity, lower 4 h urinary excretion and higher normal bone-to-background ratio. Assessment of overall image quality also favored 99mTc MDP; apparently the normal skeleton is better visualized with this agent. The total number of lesions seen (18) was not large enough to allow critical comparison of relative lesion-detecting efficacy. Discrepancies between the 2 agents were seen, suggesting additional study of the relative lesion-detecting efficacy of the 2 bone agents.

This publication has 0 references indexed in Scilit: