Probiotics and Gastrointestinal Infections
Open Access
- 1 January 2008
- journal article
- review article
- Published by Hindawi Limited in Interdisciplinary Perspectives on Infectious Diseases
- Vol. 2008, 1-10
- https://doi.org/10.1155/2008/290769
Abstract
Gastrointestinal infections are a major cause of morbidity and mortality worldwide, particularly in developing countries. The use of probiotics to prevent and treat a variety of diarrheal diseases has gained favor in recent years. Examples where probiotics have positively impacted gastroenteritis will be highlighted. However, the overall efficacy of these treatments and the mechanisms by which probiotics ameliorate gastrointestinal infections are mostly unknown. We will discuss possible mechanisms by which probiotics could have a beneficial impact by enhancing the prevention or treatment of diarrheal diseases.Keywords
Funding Information
- National Institutes of Health (N01-AI-30058, R01 DK065075, P30 DK56338, R21 AT003482, R01 AT004326)
This publication has 85 references indexed in Scilit:
- Inhibition of Neisseria gonorrhoeae Epithelial Cell Interactions by Vaginal Lactobacillus SpeciesInfection and Immunity, 2008
- Bile Salts and Glycine as Cogerminants for Clostridium difficile SporesJournal of Bacteriology, 2008
- Lactobacillus rhamnosus Strain GG Prevents Enterohemorrhagic Escherichia coli O157:H7-Induced Changes in Epithelial Barrier FunctionInfection and Immunity, 2008
- Genomic and Genetic Characterization of the Bile Stress Response of ProbioticLactobacillus reuteriATCC 55730Applied and Environmental Microbiology, 2008
- Probiotics Affect Virulence-Related Gene Expression in Escherichia coli O157:H7Applied and Environmental Microbiology, 2007
- The Early Response to Acid Shock inLactobacillus reuteriInvolves the ClpL Chaperone and a Putative Cell Wall-Altering EsteraseApplied and Environmental Microbiology, 2007
- Induction of Human β-Defensin 2 by the ProbioticEscherichia coliNissle 1917 Is Mediated through FlagellinInfection and Immunity, 2007
- Bacteriocin production as a mechanism for the antiinfective activity of Lactobacillus salivarius UCC118Proceedings of the National Academy of Sciences, 2007
- Effective prophylaxis against rotavirus diarrhea using a combination of Lactobacillus rhamnosus GG and antibodiesBMC Microbiology, 2007
- Pathogenic Escherichia coliNature Reviews Microbiology, 2004