Clinical Significance of Skin Biopsies in the Diagnosis and Management of Graft-vs-Host Disease in Early Postallogeneic Bone Marrow Transplantation
Open Access
- 1 June 2000
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Dermatology
- Vol. 136 (6) , 717-721
- https://doi.org/10.1001/archderm.136.6.717
Abstract
GRAFT-VS-HOST disease (GVHD) after allogeneic bone marrow transplantation (BMT) is an immunological process in which activated donor lymphocytes mount an attack on recipient tissues. This process involves secretion of cytokines and recruitment of additional inflammatory cells. The severity of acute GVHD is one of the most important prognostic factors that predict outcome of BMT.1Keywords
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