Protein Synthesis Enhanced in the Liver of Rats Force-Fed a Threonine-Devoid Diet
- 6 November 1964
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 146 (3645) , 766-768
- https://doi.org/10.1126/science.146.3645.766
Abstract
There is enhanced incorporation of leucine-C14 into proteins in cell-free preparations from livers of young rats force-fed a threonine-devoid diet for 3 days. This increased protein synthesis in the liver is related predominantly to enhanced activity of ribosomes. The aggregates of liver ribosomes (ergosonmes or polysomes) as measured in a sucrose gradient indicated a shift from lighter toward heavier ergosomes with a decrease in monomers.Keywords
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