Acute Self‐Poisoning with Tricyclic Antidepressants in 295 Consecutive Patients Treated in an ICU
- 30 December 1984
- journal article
- research article
- Published by Wiley in Acta Anaesthesiologica Scandinavica
- Vol. 28 (6) , 666-670
- https://doi.org/10.1111/j.1399-6576.1984.tb02142.x
Abstract
Clinical findings on admission to hospital and outcome in 295 consecutive patients with severe tricyclic antidepressant self-poisoning treated in an ICU [intensive care unit] are presented. Cerebral depression was observed in 92%, convulsions in 23% and respiratory failure was present in 72%. Cardiovascular function was impaired in 44% and an abnormal ECG was found in 57%. Cardiac arrest was treated in 14 patients (6%) of whom 7 were resuscitated. The mortality rate was 2%. All patients were artifically ventilated. A beneficial effect of respiratory alkalosis on cardiac arrhythmias is supported.Keywords
This publication has 17 references indexed in Scilit:
- Acute Propoxyphene Self‐Poisoning in 222 Consecutive PatientsActa Anaesthesiologica Scandinavica, 1984
- Antidepressant drugsPublished by Elsevier ,1982
- Pharmacokinetics of Drug OverdoseClinical Pharmacokinetics, 1981
- Cardiovascular manifestations of tricyclic antidepressant overdoseAmerican Heart Journal, 1980
- Respiratory Distress Syndrome and Thrombotic, Non‐Bacterial Endocarditis after Amitriptyline OverdoseActa Medica Scandinavica, 1977
- SODIUM BICARBONATE AND TRICYCLIC-ANTIDEPRESSANT POISONINGThe Lancet, 1976
- Tricyclic Antidepressant OverdosageClinical Toxicology, 1976
- Tricyclic Antidepressive Poisoning with Special Reference to Cardiac ComplicationsActa Anaesthesiologica Scandinavica, 1975
- CARDIOVASCULAR EFFECTS OF POISONING WITH TRICYCLIC ANTIDEPRESSANTSActa Medica Scandinavica, 1974
- Cardiovascular complications of antidepressant therapy: Interactions at the adrenergic neuronAmerican Heart Journal, 1972