Enhanced accumulation of tau in doubly transgenic mice expressing mutant βAPP and presenilin-1
- 13 June 2006
- journal article
- Published by Elsevier in Brain Research
- Vol. 1094 (1) , 192-199
- https://doi.org/10.1016/j.brainres.2005.12.134
Abstract
No abstract availableKeywords
Funding Information
- Ministry of Education, Culture, Sports, Science and Technology
- Ministry of Health, Labour and Welfare (15390273, 15590879, 16390251, 16500213, 16590829)
This publication has 34 references indexed in Scilit:
- A novel presenilin 1 mutation associated with Pick's disease but not β‐amyloid plaquesAnnals of Neurology, 2004
- Spherical aggregates of β-amyloid (amylospheroid) show high neurotoxicity and activate tau protein kinase I/glycogen synthase kinase-3βProceedings of the National Academy of Sciences, 2003
- Increased tau phosphorylation but absence of formation of neurofibrillary tangles in mice double transgenic for human tau and Alzheimer mutant (M146L) presenilin-1Neuroscience Letters, 2002
- Formation of Neurofibrillary Tangles in P301L Tau Transgenic Mice Induced by Aβ42 FibrilsScience, 2001
- Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenesNature Medicine, 1998
- Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid β-protein in both transfected cells and transgenic miceNature Medicine, 1997
- Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic MiceScience, 1996
- Analysis of phosphorylation of tau with antibodies specific for phosphorylation sitesNeuroscience Letters, 1995
- Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor proteinNature, 1995
- A preparation of Alzheimer paired helical filaments that displays distinct tau proteins by polyacrylamide gel electrophoresis.Proceedings of the National Academy of Sciences, 1990