Effect of amphetamine on saccadic and smooth pursuit eye movements
- 1 February 1983
- journal article
- research article
- Published by Springer Nature in Psychopharmacology
- Vol. 79 (2-3) , 190-192
- https://doi.org/10.1007/bf00427810
Abstract
Healthy volunteers received single oral or intravenous doses of d-amphetamine sulphate (15 mg) and placebo in a double blind randomized design. Peak velocity of horizontal saccadic eye movements, saccade duration, saccade reaction time and smooth pursuit velocity were measured at intervals up to 1 h (IV) and 6 h (oral) after drug administration. Amphetamine produced no significant effect on saccadic and smooth-pursuit eye movements after oral administration. However, intravenous amphetamine abolished the effect of fatigue on saccadic movements and significantly (P<0.01) shortened saccadic reaction time.Keywords
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