LABELING OF PLATELETS WITH OXINE COMPLEXES OF TC-99M AND IN-111 .1. INVITRO STUDIES AND SURVIVAL IN RABBIT
- 1 January 1978
- journal article
- research article
- Vol. 19 (5) , 483-487
Abstract
99mTc oxine and 111In oxine were used to study the effects in the rabbit of various parameters on platelet labeling and the in vivo survival of platelets harvested by 4 different methods. For 111In oxine, platelet labeling in saline produces much higher efficiencies (90%) than labeling in the presence of plasma (20%), with no significant shortening of in vivo survival (1% survival at 5.9 days). For 99mTc oxine, labeling efficiencies are considerably lower (30%) and survival is shorter (1% survival at 3.8 days). For both radioagents, a 30 min labeling incubation at room temperature is suggested.This publication has 5 references indexed in Scilit:
- USE OF CALCIUM CHELATING-AGENTS AND PROSTAGLANDIN-E1 TO ELIMINATE PLATELET AND WHITE BLOOD-CELL LOSSES RESULTING FROM HEMOPERFUSION THROUGH UNCOATED CHARCOAL, ALBUMIN-AGAROSE GEL, AND NEUTRAL AND CATION-EXCHANGE RESINS1977
- EVALUATION OF IN-111 AS A NEW HIGH PHOTON YIELD GAMMA-EMITTING PHYSIOLOGICAL PLATELET LABEL1977
- Indium-111 labeled platelets: Studies on preparation and evaluation of in vitro and in vivo functionsThrombosis Research, 1976
- SURVEY OF RADIOACTIVE AGENTS FOR INVITRO LABELING OF PHAGOCYTIC LEUKOCYTES .2. PARTICLES1976
- SURVEY OF RADIOACTIVE AGENTS FOR INVITRO LABELING OF PHAGOCYTIC LEUKOCYTES .1. SOLUBLE AGENTS1976