Decreased Affinity of PBP3 to Methicillin in a Clinical Isolate ofStaphylococcus epidermidiswith Borderline Resistance to Methicillin and Free of themecAGene
- 1 September 2001
- journal article
- research article
- Published by Mary Ann Liebert Inc in Microbial Drug Resistance
- Vol. 7 (3) , 297-300
- https://doi.org/10.1089/10766290152652855
Abstract
Analysis of the antibiotic binding capacity of penicillin-binding proteins (PBPs) in a group of clinical isolates of Staphylococcus epidermidis suggests that the increased level of resistance to methicillin (MIC 4.0 μg/ml) in an isolate free of the mecA gene is due to the decreased binding capacity of PBP3.Keywords
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