Re: Reversal of Relation Between Body Mass and Endogenous Estrogen Concentrations With Menopausal Status
Open Access
- 5 March 1997
- journal article
- research article
- Published by Oxford University Press (OUP) in JNCI Journal of the National Cancer Institute
- Vol. 89 (5) , 396-397
- https://doi.org/10.1093/jnci/89.5.396
Abstract
The risk of breast cancer may be decreased in obese premenopausal women but increased in obese postmenopausal women. Potischman et al. ( 1 ) recently evaluated the relation of body mass index (BMI, kg/m 2 ) and hormonal profiles in 88 premenopausal and 210 postmenopausal control subjects from a study of endometrial cancer. They reported a significant decrease in sex hormone binding globulin (SHBG) concentrationas BMI increased in both menopausal groups. As BMI increased, total estradiol increased significantly in postmenopausal women but decreased in premenopausal women, significantly so during the follicular phase. We have repeated these analyses in another dataset.Keywords
This publication has 3 references indexed in Scilit:
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- Reversal of Relation Between Body Mass and Endogenous Estrogen Concentrations With Menopausal StatusJNCI Journal of the National Cancer Institute, 1996
- Measurement of Serum LH, FSH, Estradiol and Progesterone in Disorders of the Human Menstrual Cycle: The Inadequate Luteal PhaseJournal of Clinical Endocrinology & Metabolism, 1974