Incidence of Hypospadia and Epispadia in Chromatin-positive Men
- 24 April 2009
- journal article
- Published by Hindawi Limited in Andrologia
- Vol. 7 (3) , 237-239
- https://doi.org/10.1111/j.1439-0272.1975.tb00935.x
Abstract
There are described some results of examination of three patients with a Klinefelter's syndrome two of whom had a heavy form of hypospadia, and one suffered from epispadia. The disturbances of penis development are explained, with respect to findings in adult age, by the insensibility of target tissues to the effect of testicular androgen. This insensibility was already acting in the third month of intrauterine life of the fetus.Keywords
This publication has 2 references indexed in Scilit:
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- The relationship between the development of gonads and external genitals in human fetusesAmerican Journal of Obstetrics and Gynecology, 1968