A case of eruptive keratoacanthoma treated by oral etretinate

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Abstract
A 63-yr-old woman with eruptive keratoacanthomas on sun-exposed skin is reported. Attempts were made to produce lesions by the application of a tumor homogenate to the scratched skin, followed by UV-B irradiation; this was positive in 2 out of 3 sites, but these factors were probably non-specific stimuli. Treatment with oral etretinate led to most of the tumors disappearing within a month. Recurrence was seen on stopping the drug. Recommencement of therapy followed by a maintenance dose of 10 mg on alternate days, has been associated with freedom from the skin lesions.

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