ABNORMAL ESOPHAGEAL PRESSURES IN REFLUX ESOPHAGITIS - CAUSE OR EFFECT

  • 1 September 1986
    • journal article
    • research article
    • Vol. 81  (9) , 744-746
Abstract
Thirteen patients with gastroesophageal reflux disease underwent esophageal manometric evaluation during acute exacerbations and disease remission to evaluate lower esophageal sphincter and peristaltic pressure in response to treatment. No change was noted in lower esophageal sphincter pressure (15.2 .+-. 2.6 mg versus 14.3 .+-. 1.8 mm Hg) or peristaltic pressure (64.1 .+-. 6.9 versus 62.1 .+-. 7/8 mm Hg) with remission while both lower esophageal sphincter pressure and distal amplitude were lower in reflux patients than controls (p < 0.05). Short-term treatment resulting in endoscopic and symptom improvement of gastroesophageal reflux disease does not appear to improve lower esophageal sphincter and peristaltic pressure.

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