Homocysteine, Oxidative Stress, and Vascular Disease
- 15 June 1997
- journal article
- research article
- Published by Taylor & Francis in Hospital Practice
- Vol. 32 (6) , 81-92
- https://doi.org/10.1080/21548331.1997.11443510
Abstract
First recognized in patients with rare inborn errors of metabolism, the association of elevated plasma homocysteine concentrations with atherosclerosis and thrombosis now seems relevant to the general population as well. The mechanism of injury appears to involve oxidative damage to endothelial cells. Vitamin supplementation can normalize homocysteine levels and may lower the incidence of atherothrombotic vascular disease.Keywords
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