10-Propargylaminopterin and alkyl homologs of methotrexate as inhibitors of folate metabolism
- 1 July 1982
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 25 (7) , 877-880
- https://doi.org/10.1021/jm00349a024
Abstract
Note: In lieu of an abstract, this is the article's first page.This publication has 5 references indexed in Scilit:
- Syntheses of .alpha.- and .gamma.-substituted amides, peptides, and esters of methotrexate and their evaluation as inhibitors of folate metabolismJournal of Medicinal Chemistry, 1982
- Folate analogs altered in the C9-N10 bridge region. 18. Synthesis and antitumor evaluation of 11-oxahomoaminopterin and related compoundsJournal of Medicinal Chemistry, 1981
- A potent antitumour quinazoline inhibitor of thymidylate synthetase: Synthesis, biological properties and therapeutic results in micePublished by Elsevier ,1981
- Analog specific aberrancies in antifolate inhibition of L1210 cell dihydrofolate reductaseBiochemical Pharmacology, 1980
- TISSUE PHARMACOKINETICS, INHIBITION OF DNA-SYNTHESIS, AND TUMOR-CELL KILL AFTER HIGH-DOSE METHOTREXATE IN MURINE TUMOR MODELS1976