Variation in the Virulence of Strains of Mycoplasma pulmonis Related to Susceptibility to Killing by Macrophages in vivo
Open Access
- 1 October 1979
- journal article
- research article
- Published by Microbiology Society in Journal of General Microbiology
- Vol. 114 (2) , 289-294
- https://doi.org/10.1099/00221287-114-2-289
Abstract
Summary: The virulence of five strains of Mycoplasma pulmonis, as judged by their ability to survive in the respiratory tract and induce pneumonia in CBA mice, was related to the ability of viable organisms to persist in the peritoneal cavity. This appeared to be the result of differences in the ability of the strains to resist killing by peritoneal macrophages in vivo. It is suggested that resistance to phagocytosis by macrophages is an important determinant of virulence for M. pulmonis.This publication has 8 references indexed in Scilit:
- The Effect of Pneumonia Induced in Mice with Mycoplasma pulmonis on Resistance to Subsequent Bacterial Infection and the Effect of a Respiratory Infection with Sendai Virus on the Resistance of Mice to Mycoplasma pulmonisJournal of General Microbiology, 1978
- Protective Effect of Vaccines on Mycoplasma pulmonis -Induced Respiratory Disease of MiceInfection and Immunity, 1977
- Interaction of Mycoplasma dispar and Mycoplasma agalactiae subsp. bovis with bovine alveolar macrophages and bovine lacteal polymorphonuclear leukocytesInfection and Immunity, 1976
- Pathogenicity of certain mycoplasma species in the bovine mammary glandResearch in Veterinary Science, 1976
- Pneumonia due to Mycoplasma in Gnotobiotic Mice II. Localization of Mycoplasma pulmonis in the Lungs of Infected Gnotobiotic Mice by Electron MicroscopyJournal of Bacteriology, 1966
- EXPERIMENTAL INFECTION WITH MYCOPLASMA PNEUMONIAE (EATON'S AGENT)The Journal of Experimental Medicine, 1965
- THE ROLE OF THE ALVEOLAR MACROPHAGE IN THE CLEARANCE OF BACTERIA FROM THE LUNGThe Journal of Experimental Medicine, 1964
- SPECIFICITY OF CYTOTOXIC ACTION OF SILICA-A STUDY IN VITRO1963