Creatine Kinase-MB
Open Access
- 1 May 1992
- journal article
- Published by Oxford University Press (OUP) in Laboratory Medicine
- Vol. 23 (5) , 298-302
- https://doi.org/10.1093/labmed/23.5.298
Abstract
Creatine kinase (CK)-MB is the enzyme currently used as the definitive serum marker for the diagnosis or exclusion of acute myocardial infarction (AMI). This article reviews the characteristics of CK-MB, the methods and limitations of the new monoclonal anti-CK-MB antibody-based immunoassays, information on the diagnostic accuracy, clinical implications of serial and single enzyme levels, and recommendations for the optimal use of CK-MB. In addition, the role of serum CK-MB in monitoring reperfusion following thrombolytic therapy for patients with AMI is discussed.Keywords
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