Abstract
The efficiency in inducing cation permeability of vacidin A, candicidin D and amphotericin B was compared on small and large lipidic vesicles. Amphotericin B is 2 times less effective on large than on small vesicles. Vacidin A and candicidin D are .apprx. 10 times more effective on large than on small vesicles. These data are consonant with what is observed on living cells.