An Inborn Defect of Intestinal Absorption of Certain Monosaccharides

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Abstract
A patient with symptoms closely resembling those of disaccharide intolerance but in whom there was defective intestinal absorption of certain monosaccharides is described. The monosaccharides affected were those described as absorbed "actively" against a concentration difference, and included glucose, galactose, and 3-0-methyl glucose. Disaccharides containing any of these monosaccharides also caused similar symptoms. The passively absorbed sugar fructose was handled normally, and comprised the chief carbohydrate content of the child''s diet. Only 2 other reports of such patients are available, but the condition is familial and probably represents another inborn error of carbohydrate metabolism.