Protective Action of Anoxic Anoxia Against Total Body Roentgen Irradiation of Mammals

Abstract
Male and female rats (avg. wt. 170 g.), Wistar strain, were exposed to 600 r total body irradiation in one exposure (radiation factors 250 kv 15 ma., 160 to 180 r/min., h.v.l. 1.85 mm. Cu). Anoxia was induced by low O2 tension or NaCN. The LD50/30 days for rats irradiated in 5% 02 increased from 600 r to 1200-1400 r. No protection was found in rats made anoxic by NaCN.