CORRELATION OF PITUITARY AND TESTICULAR RESPONSES TO STIMULATION TESTS IN CRYPTORCHID CHILDREN
- 1 November 1977
- journal article
- research article
- Published by Oxford University Press (OUP) in Acta Endocrinologica
- Vol. 86 (3) , 641-650
- https://doi.org/10.1530/acta.0.0860641
Abstract
LH-RH [luteinizing hormone releasing hormone] test and HCG [human chorionic gonadotropin] stimulation test were performed in 154 cryptorchid boys aged 1 mo.-15 yr (64 unilateral and 90 bilateral). Basal plasma LH levels and LH response to LH-RH were significantly lower from infancy to early puberty in cryptorchids compared with controls. Basal FSH levels and FSH response to LH-RH were normal. The post-HCG rise of plasma testosterone was reduced until mid-puberty. A significant positive correlation was found between post-HCG testosterone levels and pre- and post-LH-RH levels of LH. This correlation suggests that testicular maldescent and the decreased ability of Leydig cells to respond to a short course of HCG may result from an early defect or a delay of pituitary LH secretion.This publication has 4 references indexed in Scilit:
- PITUITARY LH AND FSH AND TESTOSTERONE SECRETION IN INFANTS WITH UNDESCENDED TESTESActa Endocrinologica, 1977
- HYPOPHYSO-GONADAL FUNCTION IN THE CRYPTORCHID CHILD: DIFFERENCES BETWEEN UNILATERAL AND BILATERAL CRYPTORCHIDSActa Endocrinologica, 1976
- Plasma Androgen Response to hCG Stimulation in Prepubertal Boys with Hypospadias and CryptorchidismJournal of Clinical Endocrinology & Metabolism, 1976
- FSH. I. Evidence for Its Mediating Role on Testosterone Secretion in Cryptorchidism1Journal of Clinical Endocrinology & Metabolism, 1973