Benzodiazepine Binding Site-Interactive Flavones fromScutellaria baicalensisRoots
- 1 August 1998
- journal article
- letter
- Published by Georg Thieme Verlag KG in Planta Medica
- Vol. 64 (06) , 571-572
- https://doi.org/10.1055/s-2006-957517
Abstract
A benzodiazepine binding assay directed separation led to the identification of 3 flavones baicalein (1), oroxylin A (2), and skullcapflavone II (3) from the water extract of Scutellaria baicalensis root. Compounds 1, 2, and 3 interacted with the benzodiazepine binding site of GABAA receptors with a Ki value of 13.1, 14.6 and 0.36 µmol/L, respectively.Keywords
This publication has 0 references indexed in Scilit: