Benefits and limitations of testing for resistance to HIV drugs
Open Access
- 25 February 2004
- journal article
- review article
- Published by Oxford University Press (OUP) in Journal of Antimicrobial Chemotherapy
- Vol. 53 (4) , 555-557
- https://doi.org/10.1093/jac/dkh157
Abstract
Since drug resistance was first described in HIV in 1989, great progress has been made in our understanding of its genetic basis and molecular mechanisms. Despite these advances and the introduction of many new antiretroviral drugs, resistance remains prevalent. The types of drug resistance tests and their relative advantages and disadvantages are reviewed. How and when these tests should be used to inform HIV clinical practice and their place in anti-HIV drug development are considered.Keywords
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