Polymorphisms of CYP2C19 and CYP2D6 in Israeli Ethnic Groups
- 1 January 2004
- journal article
- Published by Springer Nature in American Journal of PharmacoGenomics
- Vol. 4 (6) , 395-401
- https://doi.org/10.2165/00129785-200404060-00006
Abstract
Background The cytochrome P450 isoenzymes CYP2C19 and CYP2D6 catalyze reactions involved in the metabolism of many widely used drugs. Their polymorphisms give rise to important interindividual and...Keywords
This publication has 26 references indexed in Scilit:
- Pharmacogenetics of cytochrome P4502D6: genetic background and clinical implicationEuropean Journal of Clinical Investigation, 2003
- Comparison of Two CYP2D6 Genotyping Methods and Assessment of Genotype-Phenotype RelationshipsClinical Chemistry, 2003
- Pharmacogenetics of the major polymorphic metabolizing enzymesFundamental & Clinical Pharmacology, 2003
- Molecular genetics of CYP2D6: Clinical relevance with focus on psychotropic drugsBritish Journal of Clinical Pharmacology, 2002
- Pharmacogenetics: an opportunity for a safer and more efficient pharmacotherapyJournal of Internal Medicine, 2001
- CYP2D6 Genotyping as an alternative to phenotyping for determination of metabolic status in a clinical trial settingAAPS PharmSci, 2000
- Optimization of cytochrome P4502D6 (CYP2D6) phenotype assignment using a genotyping algorithm based on allele frequency dataPharmacogenetics and Genomics, 1999
- Assessment of the predictive power of genotypes for the in-vivo catalytic function of CYP2D6 in a German populationPharmacogenetics, 1998
- Prevalence of CYP2D6 gene duplication and its repercussion on the oxidative phenotype in a white population*Clinical Pharmacology & Therapeutics, 1995
- Simultaneous Determination of Dextromethorphan and Three Metabolites in Plasma and Urine Using High-Performance Liquid Chromatography with Application to Their Disposition in ManTherapeutic Drug Monitoring, 1990