SEASONAL RESPONSE OF FOLLICLES IN THE OVARIES OF THE BATMYOTISGRISESCENS TO PREGNANCY URINE GONADOTROPHIN

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Abstract
INTRODUCTION THE ovarian response to gonadotrophin depends upon the state of the ovary as well as upon the nature of the hormone and its method of administration. Previous studies (Guthrie and Jeffers, 1938) indicated that bats of the genus Myotis were useful for ovarian studies. Since bats have an annual estrous cycle and mature but a single ovum each year, factors conditioning follicular growth can be more easily distinguished than in polyestrous animals in which overlapping of phases occurs in the ovaries. Cytological studies of ovaries of normal bats throughout the estrous cycle have demonstrated variations in the total number of follicles and, of more significance, variations in the volume of the follicle-oocyte system (Guthrie, Jeffers, and Smith, 1951). The present paper considers the responsiveness of the ovary to PU gonadotrophin at various stages of the estrous cycle.