Penetration of sulbactam-ampicillin and clavulanic acid-amoxicillin into the pelvic peritoneum
Open Access
- 1 July 1985
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 28 (1) , 165-166
- https://doi.org/10.1128/aac.28.1.165
Abstract
Sixteen patients were given single intravenous injections of ampicillin (0.5 g) with sulbactam (0.5 g), and 15 patients were given amoxicillin (1 g) with clavulanic acid (0.2 g) before elective laparoscopy. At 2 h after dosing, the concentrations of the four compounds in serum and in the peritoneal fluid from the Pouch of Douglas and the ratio of each combination reached levels shown to be effective for antimicrobial activity in vitro.Keywords
This publication has 3 references indexed in Scilit:
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- Anaerobic infections of the female genital tract: Bacteriologic and therapeutic aspectsAmerican Journal of Obstetrics and Gynecology, 1973