Prediction of probable Alzheimer's disease in memory-impaired patients

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Abstract
Previously, we found that measures of delayed recall and recognition memory significantly improved the utility of apolipoprotein E (ApoE) in predicting who among a sample of memory-impaired patients would develop AD over a 2-year period. [4] We did not examine the role of other neuropsychological predictors in this study. Petersen et al. [5] found that ApoE was the best predictor of dementia in patients with mild cognitive impairment when compared with a mental status examination, [6] the Dementia Rating Scale [7] (DRS) and a measure of free and cued recall. However, as with the Bronx Aging Study, the investigators were interested in predicting dementia of any etiology, and the predictor tests were also used for the purposes of diagnosis.