Lanthanoid Triflate Catalyzed Conjugate Addition of Amines to α, β-Unsaturated Esters. A Facile Route to Optically Active β-Lactam
- 1 May 1994
- journal article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 23 (5) , 827-830
- https://doi.org/10.1246/cl.1994.827
Abstract
Catalytic amount of lanthanoid(III) triflates promoted the conjugate addition of amines to 2-alkenoic acid esters to give β-amino esters. The reaction of benzylamine with α,β-unsaturated esters containing a stereogenic center at γ-position proceeded diastereoselectivity to yield optically active β-lactam precursors.This publication has 15 references indexed in Scilit:
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