Caffeine-resistant mutants ofCaenorhabditis elegans
- 14 April 1987
- journal article
- research article
- Published by Hindawi Limited in Genetics Research
- Vol. 49 (2) , 105-110
- https://doi.org/10.1017/s0016672300026896
Abstract
Summary: Wild-typeCaenorhabditis elegansfails to reach adulthood if L1 larvae are incubated in the presence of 30 mM or greater concentrations of caffeine. Eleven mutants have been isolated in which caffeine has a less pronounced effect on development. The mutations are recessive, define two genes, and have been mapped. The mechanism(s) of resistance is unknown.This publication has 25 references indexed in Scilit:
- The fate of chronically consumed caffeine in the monkey (Macaca fascicularis)Fundamental and Applied Toxicology, 1985
- On the Mechanism of Action of Theophylline and CaffeineActa Medica Scandinavica, 1985
- Caffeine alone causes DNA damage in Chinese hamster ovary cells.Cell Structure and Function, 1985
- UV IRRADIATION OF WILD TYPE AND RADIATION‐SENSITIVE MUTANTS OF THE NEMATODE Caenorhabditis elegans: FERTILITIES, SURVIVAL, AND PARENTAL EFFECTSPhotochemistry and Photobiology, 1984
- A method for the isolation of longevity mutants in the nematode Caenorhabditis elegans and initial resultsMechanisms of Ageing and Development, 1983
- Growth and death of hela cells in the presence of caffeineJournal of Cellular Physiology, 1982
- CaffeineAnnual Review of Nutrition, 1982
- CaffeineMutation Research/Reviews in Genetic Toxicology, 1977
- The life cycle of the nematode Caenorhabditis elegansDevelopmental Biology, 1976
- The occurrence of suppressors in caffeine-resistant mutants from E. Coli K12Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1969