Effect of Angiotensin-Converting Enzyme Inhibition on Myocardial Fibrosis and Function in Hypertrophied and Failing Myocardium From the Spontaneously Hypertensive Rat
- 2 December 1997
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation
- Vol. 96 (11) , 4002-4010
- https://doi.org/10.1161/01.cir.96.11.4002
Abstract
Background After a period of stable hypertrophy, male spontaneously hypertensive rats (SHR) develop heart failure between 18 to 24 months of age, with depression of active myocardial function and i...Keywords
This publication has 21 references indexed in Scilit:
- The spontaneously hypertensive rat as a model of the transition from compensated left ventricular hypertrophy to failureJournal of Molecular and Cellular Cardiology, 1995
- Cardiac angiotensin converting enzyme and myocardial fibrosis in the ratCardiovascular Research, 1994
- Collagen Metabolism in Cultured Adult Rat Cardiac Fibroblasts: Response to Angiotensin II and AldosteroneJournal of Molecular and Cellular Cardiology, 1994
- Collagen Network of the Myocardium: Function, Structural Remodeling and Regulatory MechanismsJournal of Molecular and Cellular Cardiology, 1994
- DNA synthesis in the non-infarcted cardiac interstitium after left coronary artery ligation in the rat: Effects of captoprilJournal of Molecular and Cellular Cardiology, 1991
- Enalapril prevents cardiac fibrosis and arrhythmias in hypertensive rats.Hypertension, 1991
- Increased rat cardiac angiotensin converting enzyme activity and mRNA expression in pressure overload left ventricular hypertrophy. Effects on coronary resistance, contractility, and relaxation.Journal of Clinical Investigation, 1990
- Cell calcium, oncogenes, and hypertrophy.Hypertension, 1990
- Effects of long-term angiotensin converting enzyme inhibition on myocardial hypertrophy in experimental aortic stenosis in the ratThe American Journal of Cardiology, 1988
- Molecular cloning of human angiotensinogen cDNA and evidence for the presence of its mRNA in rat heart.Circulation Research, 1987