Abstract
THE advent of space operations has ushered in a host of physiologic problems. Prominent among these is the selection of space-cabin atmospheres. Because of severe limitation in weight and power available to the spacecraft designer for support of human function, optimization of the atmospheric environment from both the physiologic and the engineering point of view has become a major factor in the planning of manned space programs. The following is a presentation of the significant factors in this man-machine interaction, with emphasis on the role of gas physiology.The basic physiologic and engineering requirements for selection of space-cabin atmospheres have . . .

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