Methodological Aspects on Drug Receptor Binding Analysis
- 13 March 2009
- journal article
- review article
- Published by Wiley in Acta Pharmacologica et Toxicologica
- Vol. 43, 74-78
- https://doi.org/10.1111/j.1600-0773.1978.tb03223.x
Abstract
Although drug receptors occur in relatively low concentrations, they can be visualized by the use of appropriate radioindicators. In most cases the procedure is rapid and can reach a high degree of accuracy. Specificity of the interaction is studied by competition analysis. The necessity of using several radioindicators to define a receptor population is emphasized. It may be possible to define isorecptors and drugs with selectivity for one isoreceptor.Keywords
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