Liquid-chromatographic quantification of plasma phenylalanine, tyrosine, and tryptophan.
Open Access
- 1 January 1981
- journal article
- research article
- Published by Oxford University Press (OUP) in Clinical Chemistry
- Vol. 27 (1) , 146-148
- https://doi.org/10.1093/clinchem/27.1.146
Abstract
Phenylalanine, tyrosine, and tryptophan are isolated and quantified by "high-pressure" liquid chromatography, with fluorescence detection. An isocratic mobile phase and reversed-phase column are used to provide rapid and reproducible measurement of these amino acids in as little as 1 to 2 microL of human plasma.This publication has 3 references indexed in Scilit:
- Detection of heterozygotes for phenylketonuria. Total body phenylalanine clearance and concentrations of phenylalanine and tyrosine in the plasms of fasting subjects compared.Clinical Chemistry, 1977
- MODULATION OF BRAIN TRYPTOPHAN-HYDROXYLASE ACTIVITY BY BRAIN TRYPTOPHAN CONTENT1977
- Determination of heterozygosity for phenylketonuria on the amino acid analyzerClinica Chimica Acta; International Journal of Clinical Chemistry, 1967