PARTIAL SHAM FEEDING RELEASES GASTRIN IN NORMAL HUMAN-SUBJECTS

Google Scholar
  • 1 January 1981
    • journal article
    • research article
    • Vol. 16  (1) , 13-16
Abstract
Sham feeding was studied to determine if precluded oral contact with food would release gastrin. In 16 experiments in 7 subjects, an appetizing meal was discussed or subjects were permitted to see and/or smell a meal of their choice being prepared. In response to this partial sham feeding, serum gastrin concentrations increased from 48 .+-. 5 to 57 .+-. 7 pg/ml (p < 0.005). Gastric acid output also increased significantly in response to partial sham feeding. Sham feeding evidently releases significant amounts of gastrin in healthy human subjects. This response is apparently not dependent upon the presence of food in the oral cavity.