Treatment of Muscular Dystrophy with Steroids

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Abstract
THE muscular dystrophies are a group of hereditary diseases characterized by painless, symmetrical, progressive, unremitting weakness and wasting of muscle1 for which there is no specific treatment. There are several distinct forms, progressive facioscapulohumeral, limb-girdle and myotonic, which differ in the age at onset, sex distribution, distribution of involved muscles and course of progression.The appearance of a mutant strain of mice afflicted with a hereditary malady closely resembling human muscular dystrophy2 made possible a systematic study of the effects of drugs in this disease. The administration of certain anabolic steroids or cardiac glycosides to dystrophic mice was found to . . .