Histamine in Full-Thickness Skin Autografts of Rat.

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Abstract
Summary Analyses of histamine and water content performed on full thickness auto-grafts of rat skin showed a considerable histamine release during the first 24 hours after operation. Simultaneously an increase in water content of the graft was measured. It is suggested that histamine may play a role in the early phase of repair and to survival of the graft, presumably by increasing vascular permeability.