Prostaglandin synthetase inhibitor in an infant with congenital chloride diarrhoea.
- 1 January 1980
- journal article
- case report
- Published by BMJ in Archives of Disease in Childhood
- Vol. 55 (1) , 70-72
- https://doi.org/10.1136/adc.55.1.70
Abstract
Hyper-reninaemia, hypokaluria, and hypokalaemia in an infant with congenital chloride diarrhoea improved during treatment with a prostaglandin synthetase inhibitor, ketoprofen. There was evidence of increased activity of therenin-aldosterone system when ketoprofen was stopped. It is suggested that prostaglandins may be involved in stimulating the renin-aldosterone system in congenital chloride diarrhoea.Keywords
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