Vaccinia Gangrenosa in Chronic Lymphatic Leukemia
- 1 February 1962
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of internal medicine (1960)
- Vol. 109 (2) , 205-208
- https://doi.org/10.1001/archinte.1962.03620140077012
Abstract
Since a successful smallpox vaccination is in a sense an iatrogenic disease, it is particularly unfortunate that patients with chronic lymphatic leukemia may develop a progressive necrotizing vaccinial infection (vaccinia gangrenosa) following this procedure. In the past, this complication has invariably been fatal.3 This is the report of an adult with chronic lymphatic leukemia who recovered from vaccinia gangrenosa with the aid of vaccinia immune globulin. Report of Case A 66 year old white retired postal worker was admitted to the hospital on June 22, 1959, because of weakness of 3 days' duration. He had been found to have chronic lymphatic leukemia in 1956 and had been treated with radiation and chlorambucil. One month before admission his hematocrit was 37%. He felt well until a few days before admission, taking chlorambucil, 2 mg/day. In preparation for a trip abroad, he was vaccinated by his private physician on June 17.This publication has 0 references indexed in Scilit: