Breast-Milk Hyperbilirubinemia

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Abstract
IT has become evident that several substances may interfere with the capacity of the newborn infant to conjugate bilirubin, thereby resulting in varying degrees and duration of hyperbilirubinemia in the neonatal period. Prolonged and unexplained acholuric jaundice has been observed in several breast-fed infants, but only recently has a biochemical basis for this clinical observation been described. An inhibitor substance occurring postnatally in the breast milk of some women that was clinically associated with prolonged neonatal icterus has been identified.1 This report presents an additional case of persistent indirect hyperbilirubinemia with a demonstrable inhibitor substance in the maternal breast milk, . . .