Nitrobenzyl mustard quaternary salts: A new class of hypoxia-selective cytotoxins capable of releasing diffusible cytotoxins on bioreduction
- 15 May 1994
- journal article
- Published by Elsevier in International Journal of Radiation Oncology*Biology*Physics
- Vol. 29 (2) , 317-321
- https://doi.org/10.1016/0360-3016(94)90282-8
Abstract
No abstract availableKeywords
This publication has 7 references indexed in Scilit:
- Nitrobenzyl mustard quaternary salts: a new class of hypoxia-selective cytotoxins showing very high in vitro selectivityJournal of Medicinal Chemistry, 1993
- Bioreducible mustards: a paradigm for hypoxia-selective prodrugs of diffusible cytotoxins (HPDCs)Cancer and Metastasis Reviews, 1993
- Hypoxia-selective antitumor agents. 3. Relationships between structure and cytotoxicity against cultured tumor cells for substituted N,N-bis(2-chloroethyl)anilinesJournal of Medicinal Chemistry, 1990
- Reduction of nitromin to nitrogen mustard: unscheduled DNA synthesis in aerobic or anaerobic rat hepatocytes, JB1, BL8 and Walker carcinoma cell linesCarcinogenesis: Integrative Cancer Research, 1989
- Steric effects on rates of dehalogenation of anion radicals derived from substituted nitrobenzyl halidesJournal of the American Chemical Society, 1984
- Selective toxicity of nitracrine to hypoxic mammalian cellsBritish Journal of Cancer, 1984
- Substituent effects. 6. Charged groups: a simple extension of the Hammett equationThe Journal of Organic Chemistry, 1978