CHANGES IN THE BLOOD FLOW THROUGH THE BRAIN AND MUSCLES DURING THE ARREST OF BREATHING

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Abstract
When natural or artificial ventilation of the lungs of dogs, cats, rabbits, beaver, and muskrats ceases, blood flow decreases through the muscles and increases in the brain. The change in flow is not related to change or constancy in arterial pressure, nor to mechanical influences from thoracic pressure changes. The control of the decrease in muscular flow passes through the sympathetic nerves, but not in the cervical sympathetic for the brain. Section of the vagus, depressor and carotid sinus nerves did not eliminate the response in either brain or muscle. The quickness (less than 12 secs.) and regularity of the response indicate its importance in respiration.

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