Functional significance of alterations in cardiac contractile protein isoforms
Open Access
- 1 January 1996
- journal article
- review article
- Published by Wiley in Clinical Cardiology
- Vol. 19 (1) , 9-18
- https://doi.org/10.1002/clc.4960190105
Abstract
Multiple closely related, yet distinct, isoforms exist for each of the cardiac contractile proteins. The isoform composition of the heart changes in response to developmental and physiologic cues. This paper reviews the molecular basis for cardiac contractile protein isoform diversity and the functional consequences of isoform shifts.Keywords
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