Gallbladder Bacteriology, Histology, and Gallstones

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Abstract
Unselected cholecystectomy specimens in Honolulu had positive bacterial cultures in 46.7% of 501 cases. The numbers were much greater in acute cholecystitis, in ductal obstruction, and in elderly patients. The most commonly cultured organisms were Escherichia coli, Klebsiella-Enterobacter, enterococci, Clostridium perfringens, and staphylococci. Gallstones did not influence the prevalence of positive cultures. Wound infections occurred in 11% of the men and 2% of the women. The same organism was cultured from both the wound and the gallbladder in 65% of the cases. In most of the cases where the bacteria in the wound and gallbladder differed, another organ was also removed. Gallbladder culture is a useful tool in the prophylaxis and management of wound infections. This is especially true in elderly patients, in acute cholecystitis, and with ductal obstruction.

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