Comparison of the prognostic value of left ventricular filling and peak oxygen uptake in patients with systolic heart failure
Open Access
- 15 November 2000
- journal article
- research article
- Published by Oxford University Press (OUP)
- Vol. 21 (22) , 1864-1871
- https://doi.org/10.1053/euhj.2000.2174
Abstract
Aim The aim of this prospective study was to compare the prognostic value of the mitral inflow pattern and peak oxygen uptake in patients with systolic heart failure. Background Peak oxygen uptake is a major prognostic parameter in heart failure. It is not known whether a restrictive mitral inflow pattern has similar prognostic value. Methods One hundred heart failure patients (ejection fraction Results The ejection fraction was larger in group 1 (non-restrictive pattern: E/A mitral wave ratio 2 or between 1 and 2 with E deceleration time P−1.kg−157±11 vs 75±15% of predicted values;PP=0·006), a restrictive or a fusion pattern (P=0·04) were associated with a poor outcome; the prognostic value of these Doppler variables was greater than that of ejection fraction, but remained less than peak oxygen uptake indexed by predicted values (P=0·0004). Conclusion The left ventricular filling pattern is a strong predictor of exercise capacity, and outcome, in patients with systolic heart failure and is independent of the left ventricular ejection fraction. Peak oxygen uptake remains a more powerful prognostic variable.Keywords
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