Treatment Of Acute Methylmercury Ingestion By Hemodialysis With N-Acetylcysteine (Mucomyst) Infusion And 2,3-Dimercaptopropane Sulfonate

Publisher Website
Google Scholar
Abstract
A case of acute methylmercury ingestion was treated sequentially with oral D-penicillamine, hemodialysis during N-acetylcysteine (NAC) infusion, and 2,3-dimercaptopropane sulfonate (DMPS) an experimental oral agent. Urinary organic mercury elimination rate increased almost 40-fold during and 84-fold after hemodialysis with NAC infusion, compared with elimination during initial D-penicillamine therapy. Mean clearance during hemodialysis was only 13 ml/min with an