PRE-L. E. CELL: A STAGE IN DEVELOPMENT OF THE L. E. PHENOMENON
- 1 May 1952
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Dermatology
- Vol. 65 (5) , 581-586
- https://doi.org/10.1001/archderm.1952.01530240073009
Abstract
THE PURPOSE of this paper is to describe and illustrate a new, bizarre cell which may be one of the stages in the formation of the L. E. cell. Recognition of this cell may help in the establishment of an early diagnosis of disseminated lupus erythematosus. HISTORICAL SUMMARY The original report in 1948 by Hargraves and his associates1 of the finding of a new cell, the L. E. cell, in the bone marrow of patients with acute disseminated lupus erythematosus stimulated a great deal of interest and research into the mechanism of the formation of this cell. An ever-increasing number of studies by many different groups of workers has been constantly appearing in the literature. A summary of the findings to date follows:Keywords
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