CHANGES IN THE BRAIN IN PLEXECTOMIZED DOGS
- 1 December 1937
- journal article
- other
- Published by American Medical Association (AMA) in Archives of Neurology & Psychiatry
- Vol. 38 (6) , 1224-1239
- https://doi.org/10.1001/archneurpsyc.1937.02260240104008
Abstract
Much as facts furnished by neuropathologic observations speak against the hypothesis that the origin of the cerebrospinal fluid is largely, if not exclusively, in the choroid plexus, such a hypothesis is almost generally accepted and considered by some as dogma. This attitude is due largely to conclusions which Dandy1thought he was justified in drawing from his experiments with removal of the choroid plexus in animals (plexectomy). Dandy was so carried away by the interpretations of his experiments that he did not hesitate to aver2that experimental data are much more valuable than facts furnished by pathologic research and that the latter is a "dangerous method," for it "eventually has to satisfy a number of experiments which are more or less crucial." It would probably be more rational to claim the reverse —that "crucial" experiments should satisfy the facts furnished by human pathology and that it is notKeywords
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